62STUDIES ON IMMUNOLOGICAL RATES AND EFFECT OF VAGINAL SUPPOSITORIES ON VAGINITIS INDUCTED ANIMALSPreclinical study of safety for human health is a set of chemical, physical, biological, microbiological, pharmacological, and toxicological researches. Preclinical study of medical agent (MA) is a preclinical research in laboratory environment and on animal models for determination of specific activity and safety of MA. The main task of preclinical study is: determination of MA action mechanisms, development guidance concerning to safe starting dose in clinical studies andproposals for human oriented dosage regimen, ascertainment of potential target organs as to toxicity/activity point of viewzmalenka@mail.ruResearch432014Preclinical study,Medical agent,Vaginitis,Immunological studiesDavtyan LL,Nizhenkovska ІV,Popovich VP,Maletska ZV,Zinchenko LV,Bazas VMProfessor, Head of Pharmaceutical Technology and Biopharmacy Department, Shupyk National Medical Academy of Postgraduate Education, Ukraine,Professor, Head at Department of Bioorganic, Biological and Pharmaceutical Chemistry, Dean in pharmaceutical faculty, Bogomolets National Medical University, Ukraine,Professor, Head of Pharmaceutical and Industrial TechnologyDepartment, Bogomolets National Medical University, Ukraine,Postgraduate student of Pharmaceutical Technology and Biopharmacy Department, Shupyk National Medical Academy of Postgraduate Education, Ukraine,Assistant, Department of Bioorganic, Biological and Pharmaceutical Chemistry, Bogomolets National Medical University, Ukraine, Assistant professor, Department of Oncology, Shupyk National Medical Academy of Postgraduate Education, Ukraine