41IMMUNOMODULATORY ACTIVITY OF TINOSPORA SINENSISThe present study was undertaken to evaluate the effect of some selected medicinal plants on immunomodulatory activity that comprises of screening to identify the activity of ethanolic extract of medicinal plants on humoral and cell mediated immunity (specific immune response). Experiments were conducted in vivo in Swiss albino mice. Tinospora sinensis ethanolic extract was found to enhance humoral immune response on 7th day by 12 % as compared to the standard control cyclophosphamide that exhibited 54% humoral immune response, whereas cell mediated immune response was observed with an enhancement in the values (19.27%) in comparison with controlcyclosporine (37.63%).sandhyaguggilla9@gmail.comResearch412014Tinospora sinensis Dunal,Immunomodulation,Haemagglutination titre (HT),Delayed type of hypersensitivity (DTH) responseG. Sandhyarani,K. Praveen KumarVaageswari College of Pharmacy, Karimnager, Andhra Pradesh, India, Vaagdevi College of Pharmacy, Medicinal Chemistry Research Division, Hanamkonda, Warangal, Andhra Pradesh, India